2.2 Extraction Vessel Design for Supercritical Fluid Extraction (SFE)

Here’s a comprehensive guide on Extraction Vessel Design for Supercritical Fluid Extraction (SFE):


1. Role of the Extraction Vessel

The extraction vessel is where the raw material interacts with supercritical CO₂ under controlled temperature and pressure. Its design is critical for:

  • Efficient solvent–solute contact
  • Uniform flow distribution
  • Safety under high pressure
  • Scale-up from lab → pilot → industrial operations

2. Key Design Considerations

a. Material of Construction

  • Must withstand high pressure (typically 100–600 bar) and temperature (above Tc).
  • Common materials: Stainless steel (SS 316, SS 304), Hastelloy.
  • Corrosion-resistant if solvents or modifiers are used.

b. Shape and Geometry

  • Cylindrical vessels are most common: good pressure distribution and easy fabrication.
  • Vertical orientation allows CO₂ to flow bottom-to-top or top-to-bottom.
  • Aspect ratio (height/diameter) affects flow dynamics and extraction efficiency.

c. Volume / Capacity

  • Lab-scale: 50–500 mL
  • Pilot-scale: 1–20 L
  • Industrial-scale: 50–500+ L
  • Volume depends on feedstock quantity and desired throughput.

d. Flow Design

  • Uniform CO₂ flow avoids channeling or bypassing of material.
  • Packing material or filters at inlet/outlet prevent particle clogging.
  • Distributor plates or frits can ensure even flow.

e. Temperature Control

  • Jackets or internal coils for heating (to reach supercritical temperature).
  • Thermocouples placed for uniform temperature monitoring.

f. Pressure Control & Safety

  • Designed for max operating pressure > expected pressure (safety factor 1.5–2×).
  • Equipped with:
    • Pressure relief valves
    • Burst disks
    • Pressure sensors

3. Accessories / Additional Features

FeaturePurpose
Sampling PortsTake extracts during the process
Sight Glasses (lab-scale)Monitor flow and packing
Agitation / MixingOptional for better contact in dense materials
Co-solvent Injection PortFor polar modifiers (ethanol, methanol)
Insulation / JacketMaintain uniform temperature

4. Design Considerations for Scale-Up

  • Maintain geometric similarity: height/diameter ratio consistent
  • Ensure flow distribution scales proportionally
  • Multi-vessel systems may be used for continuous extraction
  • Materials and safety systems upgraded for higher volumes

5. Summary Table

AspectDesign Requirement / Consideration
MaterialStainless steel / corrosion-resistant alloy
ShapeCylindrical, vertical preferred
CapacityLab: 50–500 mL, Pilot: 1–20 L, Industrial: 50–500+ L
Flow DistributionDistributor plates, filters, avoid channeling
Temperature ControlJackets, coils, thermocouples
Pressure ControlRated for max operating pressure, relief valves, burst disks
AccessoriesSampling ports, agitation, co-solvent injection

✅ Bottom Line:
A well-designed extraction vessel ensures uniform supercritical CO₂ contact, maintains process control, and provides safety under high-pressure conditions, directly impacting yield, selectivity, and reproducibility in SFE.


I can also create a visual schematic of an SFE extraction vessel, showing CO₂ inlet, flow distributor, packing, temperature jacket, and outlet to separator.

Do you want me to make that schematic?