4.2 Carbon sources and gelling agents 

Here’s a professional, course-ready section on Carbon Sources and Gelling Agents for COPI’s Agarwood Tissue Culture Course, designed for SOP manuals, lab training, and propagation protocols.


Carbon Sources and Gelling Agents in Aquilaria Tissue Culture


1. Importance

In vitro plant culture requires external carbon sources and gelling agents to support:

  • Energy supply for growth and differentiation
  • Proper medium consistency for explant support
  • Optimal water availability and nutrient diffusion
  • Prevention of hyperhydricity and abnormal tissue development

Proper selection of carbon sources and gelling agents is crucial for high-quality Aquilaria regeneration.


2. Carbon Sources

2.1 Common Carbon Sources

Carbon SourceTypical ConcentrationRole / Notes
Sucrose2–3% (w/v)Most widely used; stable; metabolized efficiently by Aquilaria tissues
Glucose2–3%Rapidly utilized; can cause osmotic stress if overused
Fructose2–3%Enhances certain organogenesis responses; less common
Maltose2–3%Promotes somatic embryogenesis in some woody plants
Polyols (e.g., sorbitol)1–2%Used experimentally for osmotic control and callus induction

2.2 Considerations

  • Concentration: High sugar levels → osmotic stress, browning
  • Type: Sucrose is standard; glucose or maltose used in research or for slow-growing explants
  • Interactions: Carbon source may affect PGR effectiveness and secondary metabolite production

3. Gelling Agents

3.1 Common Gelling Agents

Gelling AgentTypical ConcentrationCharacteristics / Notes
Agar0.6–0.8%Traditional, widely available, supports shoots and roots
Gelrite / Gellan gum0.2–0.3%Clear medium; less impurities; good for somatic embryogenesis
Agarose0.4–0.6%High purity; experimental use; reduces inhibitory compounds
Carrageenan / Xanthan gum0.2–0.5%Rare; used for specialized applications

3.2 Considerations

  • Medium firmness: Too soft → poor support, hyperhydricity; Too hard → poor nutrient diffusion
  • Transparency: Gelrite/gellan improves observation of explant growth
  • Impurities: High-quality gelling agents reduce toxic phenolics and heavy metal interference

4. Practical Guidelines for COPI Labs

  1. Select carbon source according to explant type:
    • Sucrose: nodal and shoot tip cultures
    • Maltose: callus and somatic embryogenesis
  2. Optimize concentration to avoid osmotic stress: 2–3% sucrose standard
  3. Choose gelling agent based on regeneration goal:
    • Agar for routine organogenesis
    • Gelrite for callus or embryo culture
  4. Mixing and sterilization:
    • Add gelling agent before autoclaving
    • Add heat-sensitive additives post-sterilization via filtration
  5. Monitor medium consistency and adjust if hyperhydricity occurs

5. Key Principles

  • Carbon source provides energy and osmotic balance
  • Gelling agent provides support and diffusion control
  • Both influence morphogenesis, root induction, and plantlet vigor
  • Customizing both according to Aquilaria species and explant type enhances survival, regeneration, and resin-yield potential

6. Course-Ready Key Statement

The careful selection and optimization of carbon sources and gelling agents are fundamental to Aquilaria tissue culture. These components control energy availability, medium structure, and water potential, directly impacting shoot/root regeneration, callus induction, and long-term plantlet health.


I can next:

  • Create a visual infographic showing carbon sources vs explant types and gelling agents
  • Include recommended concentrations for nodal, shoot tip, leaf, and hypocotyl explants
  • Make a lab SOP poster for medium preparation

Do you want me to make the infographic version next?